This tool infers potential regulatory interactions between TFs and input genes, and finds the TFs which possess over-represented targets in the input gene set. More...
The sets of high-quality binding motifs of TFs and FIMO are used to scan TF binding sites in the promoters, and an interaction is assigned if there are one or more binding sites of a TF in the promoter of a gene. The genome assembly and annotation version described in the data source are used to extract promoter sequences when the coordinates of promoters/genes or gene sequences are input. The regulations predicted from the promoter regions (defined by users) of all annotated genes will be used as the background for enrichment analysis. In addition, refined regulation prediction using previous identified footprints is supported now.
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